Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.

Abstract

INTRODUCTION Prostate apoptosis response gene-4, known as par-4, is a new proapoptotic factor functionally required but not sufficient for apoptosis. Since there is evidence from prostate cancer cells that par-4 is involved in regulation of bcl-2 we assessed expression of par-4 and bcl-2 in different populations of normal and neoplastic lymphocytes… (More)

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@article{Boehrer2001DeregulatedEO, title={Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia.}, author={Simone Boehrer and Kai Uwe Chow and Elena Puccetti and Martin Ruthardt and S Godzisard and Andrea Krapohl and Bernard F. Schneider and Dieter F Hoelzer and P. S. Mitrou and Vivek M. Rangnekar and Eckart Weidmann}, journal={The hematology journal : the official journal of the European Haematology Association}, year={2001}, volume={2 2}, pages={103-7} }