Dercum's disease (adiposis dolorosa): a report of improvement with infliximab and methotrexate

  title={Dercum's disease (adiposis dolorosa): a report of improvement with infliximab and methotrexate},
  author={Amit Kumar Singal and Jennifer J Janiga and Nicole M Bossenbroek and H W Lim},
  journal={Journal of the European Academy of Dermatology and Venereology},
  • A. Singal, J. Janiga, +1 author H. Lim
  • Published 2007
  • Medicine
  • Journal of the European Academy of Dermatology and Venereology
Adiposis Dolorosa Is More Than Painful Fat
The survey results suggest AD is a painful syndrome involving growths in all subcutaneous fat, which can be inherited or sporadic, beginning in the third decade of life, but can occur in children and is accompanied by obesity, fatigue, joint and muscle aches, and other signs and symptoms affecting multiple organ systems. Expand
Rare Forms of Lipomatosis: Dercum’s Disease and Roch-Leri Mesosomatous Lipomatosis
This review examines the available literature on Dercum’s disease and Roch-Leri mesosomatous lipomatosis and finds that low-grade fat inflammation and specific abnormalities such as hyperbasophilia deserve further investigation. Expand
Dercum's Disease: A Case Report of a Patient Having Both Type 1 and Type 2 Dercum's Disease
Dercum's disease, or adiposis dolorosa, is a rare disorder which consists of multiple, painful lipomas within the subcutaneous tissue and has a distribution mainly in the abdomen and extremities.Expand
Adiposis Dolorosa Pain Management.
While current approaches to treatment focus on surgery, opiates, and other medications, health care providers may also consider ketamine infusion, electrostimulation, and perineural injections.
Dercum’s disease (adiposis dolorosa): a review of clinical presentation and management
Dercum’s disease (adiposis dolorosa) is a rare disease of unknown etiology characterized by painful subcutaneous adipose tissue deposits with various localization over the body, associated with overweight or obesity and a variety of psychiatric disturbances. Expand
Dercum’s disease or Adiposis Dolorosa: a complex condition still awaiting full definition
Dercum’s disease (DD), also called adiposis dolorosa (AD), is known as a rare, chronic and progressive disorder characterized by multiple, subcutaneous painful adipose tissue masses. DD mainly occursExpand
Als Lipomatosen bezeichnet man gutartige, meist ohne eindeutige Auslöser auftretende Vermehrungen des Fettgewebes, oft mit typischem Verteilungsmuster. Im Gegensatz zu umschriebenen LipomenExpand
These are benign proliferations of adipose tissue, often with typical distribution patterns, which usually occur without clear causes and are not surrounded by a fibrous pseudocapsule. Expand


Targets for TNF-α-induced lipolysis in human adipocytes
The results suggest that TNF-α-mediated lipolysis is dependent on down-regulation of PLIN expression via p44/42 and JNK, which could be an important mechanism for the development of insulin resistance in both obesity and cachexia. Expand
Fine-needle aspiration biopsy with CT guidance.
With computed tomographic guidance, 34 percutaneous fine-needle aspiration biopsies were obtained from various sites in 31 consecutive patients, resulting in a total of 34 biopsy sites, with the overall diagnostic accuracy rate was 95 percent. Expand