Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa.

@article{Monteleone2015DerangedER,
  title={Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa.},
  author={Alessio Maria Monteleone and Vincenzo di Marzo and Teresa Aveta and Fabiana Piscitelli and Riccardo Dalle Grave and Pasquale Scognamiglio and Marwan El Ghoch and Simona Calugi and Palmiero Monteleone and Mario Maj},
  journal={The American journal of clinical nutrition},
  year={2015},
  volume={101 2},
  pages={262-9}
}
BACKGROUND A dysregulation of reward mechanisms was suggested in the pathophysiology of anorexia nervosa (AN), but the role of the endogenous mediators of reward has been poorly investigated. Endocannabinoids, including anandamide and 2-arachidonoylglycerol, and the endocannabinoid-related compounds oleoylethanolamide and palmitoylethanolamide modulate food-related and unrelated reward. Hedonic eating, which is the consumption of food just for pleasure and not homeostatic need, is a suitable… CONTINUE READING
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