Deramciclane in the treatment of generalized anxiety disorder: A placebo-controlled, double-blind, dose-finding study

@article{Naukkarinen2005DeramciclaneIT,
  title={Deramciclane in the treatment of generalized anxiety disorder: A placebo-controlled, double-blind, dose-finding study},
  author={H. Naukkarinen and Roope Raassina and J. Penttinen and A. Ahokas and R. Jokinen and H. Koponen and U. Lepola and H. Kanerva and Leena Lehtonen and T. Pohjalainen and Auli Partanen and O. M{\"a}ki-Ikola and J. Rouru},
  journal={European Neuropsychopharmacology},
  year={2005},
  volume={15},
  pages={617-623}
}
Deramciclane, a camphor derivative, is a novel anxiolytic agent with a unique mechanism of action. It acts as a potent and specific antagonist at serotonin 5-HT2A/2C receptors, and exhibits anxiolytic efficacy in animal models. The aim of this double-blind, placebo-controlled, parallel-group study was to evaluate the efficacy, safety, and tolerability of a range of doses of deramciclane in patients with generalized anxiety disorder (GAD). Adult patients with a diagnosis of GAD (DSM-IV) and a… Expand
Non-Antidepressant Treatment of Generalized Anxiety Disorder.
Effect of the novel anxiolytic drug deramciclane on cytochrome P450 2D6 activity as measured by desipramine pharmacokinetics
Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone
Research in anxiety disorders: From the bench to the bedside
Agomelatine improves symptoms of generalised anxiety disorder
Current animal models of anxiety, anxiety disorders, and anxiolytic drugs
Recent developments in anxiety disorders.
Identifying HAM‐A cutoffs for mild, moderate, and severe generalized anxiety disorder
...
1
2
...

References

SHOWING 1-10 OF 28 REFERENCES
Attaining remission in generalized anxiety disorder: venlafaxine extended release comparative data.
  • D. Sheehan
  • Psychology, Medicine
  • The Journal of clinical psychiatry
  • 2001
Pattern of symptom improvement following treatment with venlafaxine XR in patients with generalized anxiety disorder.
Overview of different pharmacotherapies for attaining remission in generalized anxiety disorder.
  • J. Ballenger
  • Psychology, Medicine
  • The Journal of clinical psychiatry
  • 2001
...
1
2
3
...