Deramciclane improves object recognition in rats: Potential role of NMDA receptors

@article{Kertsz2010DeramciclaneIO,
  title={Deramciclane improves object recognition in rats: Potential role of NMDA receptors},
  author={S. Kert{\'e}sz and G. Kapus and I. Gacs{\'a}lyi and G. L{\'e}vay},
  journal={Pharmacology Biochemistry and Behavior},
  year={2010},
  volume={94},
  pages={570-574}
}
The cognition-enhancing properties of deramciclane (N,N-dimethyl-2-([(1R,4R,6S)-1,7,7-trimethyl-6-phenyl-6-bicyclo[2.2.1]heptanyl]oxy)ethanamine) and memantine (3,5-dimethyl-tricyclo[3.3.1.1(3,7)]decylamine-3,5-dimethyladamantan-1-amine) were evaluated in the novel object recognition (OR) test in the rat, while their effect in comparison with other N-methyl-D-aspartate (NMDA) receptor blockers such us MK-801 ([+]-5-methyl-10,11-dihydro-5H-dibenzocyclohepten-5,10-imine maleate) and CPP ([+/-]-3… Expand
Glutamate oxaloacetate transaminase: A new key in the dysregulation of glutamate in migraine patients
Systematic review of the pharmacological agents that have been tested against spreading depolarizations
  • A. Klass, R. Sánchez-Porras, E. Santos
  • Medicine
  • Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
  • 2018
Effects of NMDA receptor antagonists with different subtype selectivities on retinal spreading depression
Object recognition testing: Statistical considerations

References

SHOWING 1-10 OF 41 REFERENCES
Deramciclane inhibits N-methyl-D-aspartate receptor function
Memantine and recognition memory: possible facilitation of its behavioral effects by the nitric oxide (NO) donor molsidomine.
The triggering of spreading depression in the chicken retina: a pharmacological study
Pre- or post-training administration of the NMDA receptor blocker MK-801 impairs object recognition memory in rats
Comparison of the AMPA Antagonist Action of New 2,3-Benzodiazepines in Vitro and Their Neuroprotective Effects in Vivo
Effects of intraseptal infusions of N-methyl-d-aspartate receptor ligands on memory in an object recognition task in rats
...
1
2
3
4
5
...