Depth-resolved measurement of transient structural changes during action potential propagation.

@article{Akkin2007DepthresolvedMO,
  title={Depth-resolved measurement of transient structural changes during action potential propagation.},
  author={Taner Akkin and Chulmin Joo and Johannes F. de Boer},
  journal={Biophysical journal},
  year={2007},
  volume={93 4},
  pages={
          1347-53
        }
}
We report noncontact optical measurement of fast transient structural changes in the crustacean nerve during action potential propagation without the need for exogenous chemicals or reflection coatings. The technique, spectral domain optical coherence tomography, provides real-time cross-sectional images of the nerve with micron-scale resolution to select a specific region for functional assessment and interferometric phase sensitivity for subnanometer-scale motion detection. Noncontact optical… CONTINUE READING

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