Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha.

@article{Loftis2008DepressiveSI,
  title={Depressive symptoms in patients with chronic hepatitis C are correlated with elevated plasma levels of interleukin-1beta and tumor necrosis factor-alpha.},
  author={Jennifer M Loftis and Marilyn S. Huckans and Samantha Ruimy and David J. Hinrichs and P{\'e}ter Hauser},
  journal={Neuroscience letters},
  year={2008},
  volume={430 3},
  pages={
          264-8
        }
}
Studies suggest that cytokines have a role in the biology of depression. In this study, we evaluated depression and cytokine levels in patients with and without chronic hepatitis C (HCV) to better assess how chronic infection alters cytokines levels and may contribute to depressive symptomotology. Twenty-three adults with (n=16) and without (n=7) HCV were recruited through the Portland VA Medical Center. Research participants were excluded for current substance abuse, psychotic disorder, liver… CONTINUE READING
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