Depressive symptoms as relative and attributable risk factors for first-onset major depression.

@article{Horwath1992DepressiveSA,
  title={Depressive symptoms as relative and attributable risk factors for first-onset major depression.},
  author={Ewald Horwath and Jennifer Johnson and Gerald L. Klerman and Myrna M. Weissman},
  journal={Archives of general psychiatry},
  year={1992},
  volume={49 10},
  pages={817-23}
}
Using longitudinal data from a community study of 9900 adults drawn from four sites in the United States and interviewed twice, 1 year apart, we investigated the predictors of first-onset major depression. Using odds ratios to estimate relative risk, we found that persons with depressive symptoms, compared with those without such symptoms, were 4.4 times more likely and persons with dysthymia were 5.5 times more likely to develop a first-onset major depression during a 1-year period. The… CONTINUE READING

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