• Corpus ID: 15395198

Depressive pseudodementia - how 'pseudo' is it really?

  title={Depressive pseudodementia - how 'pseudo' is it really?},
  author={James A. Kennedy},
Depressive pseudodementia is a term commonly used to describe a condition whereby a patient experiences a cognitive deficit secondary to a primary mood disorder. This essay will explore whether depressive pseudodementia can truly be described as a dementia mimic or not. It argues that pseudodementia is closer in clinical nature to 'true' dementia, is not fully reversible, may act as a prodrome for 'true' dementia, and has an organic basis. All of these factors suggest that the term pseudo… 
Predicting Dementia Risk to Depressive Disorder Patients: A classification Approach
This study will use supervised learning techniques to construct a follow-up dementia prediction model for depressive disorder patients to assist patients and their medical staffs to predict his/her possible risk of suffering from dementia, and then develop early intervention and prevention measures.
Administration of 5-HT-1B agonist ameliorates pseudodementia induced by depression in rats.
Zolmitriptan was tested as a potential treatment for depression and associated memory loss by altering the serotonergic function at receptor level and resulted in a significant attenuation of depression and depression-associated memory impairment.
Late-Life Depressive Symptoms and Lifetime History of Major Depression: Cognitive Deficits are Largely Due to Incipient Dementia rather than Depression.
Marked cognitive impairments in old age depression should not be dismissed as "depressive pseudodementia", but require clinical attention as a possible sign of incipient dementia.
The Relationships between Gait Impairments and Activity Limitations in People with Depressive and Related Disorders Include: Depressive Pseudodementia, Hypochondriasis, Factitious Disorder, Cognitive Dysfunction and Normal Pressure Hydrocephalus
This study reviewed and ‘synthesized existing evidence on gait’ impairments in neurological disease, including Depressive, Depressive Pseudodementia, Hypochondriasis, Factitious disorder, Cognitive dysfunction and Normal Pressure Hydrocephalus.


Pseudodementia. Current concepts and future directions.
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  • Psychology, Medicine
    Archives of general psychiatry
  • 1981
Data from published reports and preliminary findings presented here suggest that intellectual impairment of patients with pseudodementia resembles subcortical dementia in many of its features.
Pseudodementia caused by severe depression
  • E. Tobe
  • Psychology, Medicine
    BMJ Case Reports
  • 2012
The diagnosis of pseudodementia may be difficult in a patient with a history of major depressive disorder, but mild cognitive improvement was noted after discontinuation of simvastatin.
Pseudodementia, a Term for its Time: The Impact of Leslie Kiloh's 1961 Paper
  • J. Snowdon
  • Psychology, Medicine
    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
  • 2011
The present article aims to honour the work and achievements of Professor Kiloh, but also to consider the impact and importance of that 1961 paper, which gave impetus to psychiatrists to focus on the potential reversibility of cognitive impairments that might be attributable to psychiatric disorders.
A Case of Mistaken Identity: Pseudodementia Is Really Predementia
  • B. Reifler
  • Psychology
    Journal of the American Geriatrics Society
  • 2000
’ The authors helped put to rest the idea that every demented patient should have a trial of antidepressant therapy by showing that the nondepressed Alzheimer’s group had no improvement in cognitive function when given an antidepressant.
Long-term outcome of depressive pseudodementia in the elderly.
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  • Psychology, Medicine
    Acta psychiatrica Scandinavica
  • 1961
To the psychiatrist there is seldom much difficulty in differentiating between the Ganser symptomatology and true dementia though this may arise when the condition is grafted onto an underlying organic psychosis.
Consideration of the relationship between depression and dementia
The literature was reviewed with regard to the relationship between Alzheimer’s dementia (AD) and depression. Then comparison was made of the case for depression as a precursor symptom of AD versus
Depression–dementia medius: Between depression and the manifestation of dementia symptoms
The clinical concept of ‘depression–dementia medius’ (which includes pseudodementia and depression in Alzheimer's disease as exemplars) is proposed, in reference to Janet's concept of psychological tension.
Depressive pseudodementia in the elderly: effectiveness of electroconvulsive therapy
A systematic review of neuropsychiatric symptoms in mild cognitive impairment and the need for a consensus in the use of assessment tools for dementia is reviewed.
  • T. Arie
  • Medicine
    British medical journal
  • 1983
The assessment of the natural history of single cerebral aneurysms that have ruptured and the incidence of early rebleeding has been over-estimated shows that older patients have low cerebral blood flow.