Depressive mania versus agitated depression: biogenic amine and hypothalamic-pituitary-adrenocortical function.

@article{Swann1994DepressiveMV,
  title={Depressive mania versus agitated depression: biogenic amine and hypothalamic-pituitary-adrenocortical function.},
  author={Alan C. Swann and Peter E. Stokes and Steven Secunda and James W. Maas and Charles L. Bowden and Nancy Berman and Stephen H. Koslow},
  journal={Biological psychiatry},
  year={1994},
  volume={35 10},
  pages={803-13}
}
The existence of mixed affective states challenges the idea of specific biological abnormalities in depression and mania. We compared biogenic amines and hypothalamic-pituitary-adrenocortical (HPA) function in mixed manic (n = 8), pure manic (n = 11), agitated bipolar depressed (n = 20), and nonagitated bipolar depressed (n = 27) inpatients (Research Diagnostic Criteria). Mixed manics met Research Diagnostic Criteria for primary manic episodes and also met criteria for major depressive episodes… CONTINUE READING