Depressive-like behavior in adolescents after maternal separation: sex differences, controllability, and GABA.

@article{Leussis2012DepressivelikeBI,
  title={Depressive-like behavior in adolescents after maternal separation: sex differences, controllability, and GABA.},
  author={Melanie P. Leussis and Nadja Freund and Heather C. Brenhouse and Britta S. Thompson and Susan Andersen},
  journal={Developmental neuroscience},
  year={2012},
  volume={34 2-3},
  pages={210-7}
}
Exposure to adversity during development is an identified risk factor for depression later in life. In humans, early adversity accelerates the onset of depressive symptoms, which manifest during adolescence. Animal studies have used maternal separation as a model of early adversity to produce adult depressive-like behaviors, but have yet to examine these… CONTINUE READING