Depression treated with imipramine and ECT: the DeCarolis study reconsidered.

  title={Depression treated with imipramine and ECT: the DeCarolis study reconsidered.},
  author={David Avery and A Lubrano},
  journal={The American journal of psychiatry},
  volume={136 4B},
The authors reevaluate a large prospective Italian study (437 patients) that compared high-dose imipramine with ECT treatment in the treatment of depression. The superiority of ECT was evident among patients with endogenous depression, and especially evident among those with delusional depression (83% improved with ECT versus 40% with imipramine) and depressions defined as severe (83% versus 35%). 

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