Depression of cytotoxicity of nonparenchymal cells in the liver after surgery.

@article{Oka1994DepressionOC,
  title={Depression of cytotoxicity of nonparenchymal cells in the liver after surgery.},
  author={Masaaki Oka and Shoichi Hazama and Minako Suzuki and Fa Sheng Wang and Kouji Shimoda and Norio Iizuka and Kenji Wadamori and Takao Suzuki and Stephen. Attwood},
  journal={Surgery},
  year={1994},
  volume={116 5},
  pages={
          877-82
        }
}
BACKGROUND The nonparenchymal cells (NPCs) of the liver have a strong cytotoxic activity. Our hypothesis is that their activity, which prevents metastases to the liver, may be impaired after operation. METHODS First, Sprague-Dawley rats underwent either a sham operation consisting of only a laparotomy (group L, n = 10), a laparotomy and resection of a portion of the small intestine (group R, n = 10) or no operation (group C, n = 10). After 2 days liver NPCs were isolated and divided into two… CONTINUE READING

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