Depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus.

@article{Sung2010DepressionlikeSI,
  title={Depression-like state in maternal rats induced by repeated separation of pups is accompanied by a decrease of cell proliferation and an increase of apoptosis in the hippocampus.},
  author={Y O Sung and M N Shin and Sehyung Cho and Hyung-Hwan Baik and Byung-Kwan Jin and H J Chang and Eun-Kyu Lee and C -K Kim},
  journal={Neuroscience letters},
  year={2010},
  volume={470 1},
  pages={86-90}
}
Stressful experiences, such as an unsatisfactory mother-infant relationship after delivery, can induce depressive disorders, and it is well-known that stressors impair memory function. The hippocampus plays a crucial role in memory processes. In the present study, we determined whether a depressed-like state induced by repeated separation of pups affects the memory capability of the maternal rats. We also determined the effects of repeated separation from pups on cell proliferation, apoptosis… CONTINUE READING

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