Depression in the elderly

@article{Alexopoulos2005DepressionIT,
  title={Depression in the elderly},
  author={George S. Alexopoulos},
  journal={The Lancet},
  year={2005},
  volume={365},
  pages={1961-1970}
}

Assessment scales for geriatric patients

Vulnerability to late-life depression is principally caused by aging-related and disease-related processes, including arteriosclerosis, inflammatory, endocrine, and immune changes that compromise the integrity of frontolimbic pathways.

Treatment of Depression in the Elderly: A Systematic Review

The selective serotonin reuptake inhibitors have replaced tricyclic antidepressants as first-line therapy when antidepressants are indicated, and electroconvulsive therapy offers a safe and effective alternative for patients refractory to or unable to tolerate antidepressant medication.

Mechanisms and treatment of late-life depression

Computerized cognitive remediation targeting functions of the cognitive control network may improve both executive functions and depressive symptoms of late-life major depression andStreamlined, stepped psychotherapies targeting behaviors assumed to result from dysfunction of brain networks implicated in late- life depression can be easy to learn and have potential for dissemination.

Depression, disability and somatic diseases among elderly.

Cerebrovascular Diseases: Post-stroke Depression and Anhedonia

Since stroke survivors frequently suffer from depression, research has focused on the incidence, phenomenology, course and risk factors of post-stroke depression, paying special attention to the biological explanatory models, such as the lesion location and vascular depression hypotheses.

Depression and cancer: an unexplored and unresolved emergent issue in elderly patients.

Neurobiology and Risk Factors of Late-Life Depression

This chapter seeks to review the research performed in this field over the last several decades, describing disturbances in fronto-subcortical function, genetic polymorphisms, chronic stress and inflammation, as well as vascular pathology.

Depression and Neurovascular Disease

Evidence from clinical, neuropsychological, neuroimaging, and post-mortem studies supports vascular depression as a distinct clinical entity and phenotype of late-life depression.
...

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