Depression in cancer: The many biobehavioral pathways driving tumor progression.

  title={Depression in cancer: The many biobehavioral pathways driving tumor progression.},
  author={Beatrice Bortolato and Thomas Hyphantis and Sara Valpione and Giulia Ida Perini and Michael Maes and Gerwyn Morris and Marta Kubera and Cristiano Andr{\'e} K{\"o}hler and Brisa Sim{\~o}es Fernandes and Brendon Stubbs and Nicholas Pavlidis and Andr{\'e} Ferrer Carvalho},
  journal={Cancer treatment reviews},
Major Depressive Disorder (MDD) is common among cancer patients, with prevalence rates up to four-times higher than the general population. Depression confers worse outcomes, including non-adherence to treatment and increased mortality in the oncology setting. Advances in the understanding of neurobiological underpinnings of depression have revealed shared biobehavioral mechanisms may contribute to cancer progression. Moreover, psychosocial stressors in cancer promote: (1) inflammation and… CONTINUE READING
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