Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.

@article{Lett2004DepressionAA,
  title={Depression as a risk factor for coronary artery disease: evidence, mechanisms, and treatment.},
  author={Heather S Lett and James A. Blumenthal and Michael A. Babyak and Andrew Sherwood and Timothy J. Strauman and Clive Robins and Mark F. Newman},
  journal={Psychosomatic medicine},
  year={2004},
  volume={66 3},
  pages={305-15}
}
OBJECTIVE The present paper reviews the evidence that depression is a risk factor for the development and progression of coronary artery disease (CAD). METHODS MEDLINE searches and reviews of bibliographies were used to identify relevant articles. Articles were clustered by theme: depression as a risk factor, biobehavioral mechanisms, and treatment outcome studies. RESULTS Depression confers a relative risk between 1.5 and 2.0 for the onset of CAD in healthy individuals, whereas depression… CONTINUE READING
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