Depression and pain.

  title={Depression and pain.},
  author={Michael J Robinson and Sara Elizabeth Edwards and Smriti Iyengar and Frank P. Bymaster and Michael T. Clark and Wayne J. Katon},
  journal={Frontiers in bioscience},
Depression and pain disorders are often diagnosed in the same patients. Here we summarize the shared pathophysiology between both disorders and the importance of addressing all symptoms in patients with comorbid pain and depression. We describe anatomical structures that are activated and/or altered in response to both depression and pain--examples include the insular cortex, the prefrontal cortex, the anterior cingulate cortex, the amygdala, and the hippocampus. Both disorders activate common… CONTINUE READING


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