Depression and immunity: clinical factors and therapeutic course.

  title={Depression and immunity: clinical factors and therapeutic course.},
  author={Steven J. Schleifer and S. E. Keller and Jacqueline A Bartlett},
  journal={Psychiatry research},
  volume={85 1},
While many reports describe associations between depressive disorders and altered immunity, findings have not been fully consistent. Diagnostic subtype, demographic factors such as age and gender, medical characteristics, and the immune measures selected for assessment may have contributed to the heterogeneous findings. In a study of 21 medically healthy young adults with major depression, we found, consistent with previous reports, evidence of increased lymphocyte activation to mitogen… CONTINUE READING