Depression and Cardiac Disease: Epidemiology, Mechanisms, and Diagnosis

@article{Huffman2013DepressionAC,
  title={Depression and Cardiac Disease: Epidemiology, Mechanisms, and Diagnosis},
  author={J. Huffman and C. M. Celano and S. Beach and S. Motiwala and J. Januzzi},
  journal={Cardiovascular Psychiatry and Neurology},
  year={2013},
  volume={2013}
}
  • J. Huffman, C. M. Celano, +2 authors J. Januzzi
  • Published 2013
  • Medicine
  • Cardiovascular Psychiatry and Neurology
  • In patients with cardiovascular disease (CVD), depression is common, persistent, and associated with worse health-related quality of life, recurrent cardiac events, and mortality. Both physiological and behavioral factors—including endothelial dysfunction, platelet abnormalities, inflammation, autonomic nervous system dysfunction, and reduced engagement in health-promoting activities—may link depression with adverse cardiac outcomes. Because of the potential impact of depression on quality of… CONTINUE READING

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