Depression: chronophysiology and chronotherapy

@article{Dridi2014DepressionCA,
  title={Depression: chronophysiology and chronotherapy},
  author={Dorr{\`a} Dridi and Amina Zouiten and Hedi ben Mansour},
  journal={Biological Rhythm Research},
  year={2014},
  volume={45},
  pages={77 - 91}
}
Depressed patients often show altered circadian rhythms, sleep disturbances, and diurnal mood variation. Decreased latency of rapid eye movement (REM) sleep, reduction in slow wave sleep, and abnormalities in the timing of REM/nonREM sleep cycles have all been reported in patients with major depressive disorder (MDD). It is thus evident that an understanding of the basic mechanisms of sleep regulation is essential, for a better analysis of the pathophysiology of depressive disorders. The aim of… Expand
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References

SHOWING 1-10 OF 151 REFERENCES
Influence of sleep-wake and circadian rhythm disturbances in psychiatric disorders.
  • D. Boivin
  • Psychology, Medicine
  • Journal of psychiatry & neuroscience : JPN
  • 2000
TLDR
The results have implications for analyzing diurnal variation of mood in unipolar and bipolar affective disorders and sleep disturbances in other major psychiatric conditions such as chronic schizophrenia. Expand
[Sleep disturbances--cause or result of depression].
TLDR
It is worthy to look closer into its regulatory effect on the disordered circadian rhythm, which is not only to give an antidepressive effect, but in a visible improvement of sleep architecture and functioning during the day. Expand
Circadian rhythm mechanisms in affective illness and in antidepressant drug action.
TLDR
Experiments indicate that abnormally advanced rhythms are not merely an epiphenomenon but play an important role in the pathogenesis of depression, leading to the hypothesis that depression occurs in susceptible individuals when a sleep-sensitive phase of the circadian system becomes advanced from the first hours of waking into the last hours of sleep and interacts with sleep to cause depression. Expand
Sleep deprivation in depression: what do we know, where do we go?
TLDR
The therapeutic effect of SD is postulated to be linked to changes in disturbed circadian- and sleep-wake-dependent phase relationships and concomitant increase of slow-wave-sleep pressure; additionally, SD-induced sleepiness may counteract the hyperarousal state in depression. Expand
Agomelatine, melatonin and depressive disorder
TLDR
It is suggested that strategies designed to bring about resynchronisation of circadian rhythms should be therapeutically effective in depression, and that the circadian alteration may be necessary but is not sufficient for an antidepressant effect. Expand
Biological rhythm disturbances in mood disorders
  • A. Wirz-Justice
  • Psychology, Medicine
  • International clinical psychopharmacology
  • 2006
TLDR
Chronobiology has provided efficacious non-pharmaceutical treatments for mood disorders (such as sleep deprivation or light therapy) as well as novel approaches to new drugs (e.g. agomelatine). Expand
Major depressive disorder, sleep EEG and agomelatine: an open-label study.
TLDR
In conclusion agomelatine improved sleep continuity and quality and normalized the distribution of SWS sleep and delta power throughout the night. Expand
The Use of Chronobiotics in the Resynchronization of the Sleep–wake Cycle
TLDR
Both in aged subjects having very minimal sleep disorders as well as in demented patients with a very severe disorganization of the sleep–wake cycle, melatonin treatment reduced the variability of sleep onset and restored sleep. Expand
Circadian rhythms in depression and recovery: Evidence for blunted amplitude as the main chronobiological abnormality
TLDR
The findings suggest that depression may be related both to a weakening of the coupling processes between internal pacemakers and to an abnormal sensitivity to environmental information. Expand
[Sleep in depression].
TLDR
Insomnia is a cardinal symptom of depression, side by side with alterations of mood and slowing down of psychomotor activities, and total deprivation of sleep for one night may damp down the depressive disorders, and so does partial sleep deprivation in the second part of the night during several days. Expand
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