Depression, cerebral atrophy, cognitive performance and incidence of dementia. Population study of 85-year-olds.

@article{Palsson1999DepressionCA,
  title={Depression, cerebral atrophy, cognitive performance and incidence of dementia. Population study of 85-year-olds.},
  author={Sigurdur P{\'a}ll Palsson and O Aevarsson and Ingmar Skoog},
  journal={The British journal of psychiatry : the journal of mental science},
  year={1999},
  volume={174},
  pages={
          249-53
        }
}
BACKGROUND Hospital-based studies suggest that depression in old age relates to organic brain changes. AIMS To determine whether these findings are confirmed in a population-based sample. METHOD A population sample of non-demented 85-year-olds (227 mentally healthy and 62 with DSM-III-R depression were given a neuropsychiatric examination and computerised tomographic scans of the brain, and followed for three years. RESULTS On the Mini-Mental State Examination, those with a low… CONTINUE READING

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