Depressed smooth muscle contractility after massive intestinal resection in rat: role of alterations in muscarinic receptor status or source of calcium for excitation-contraction coupling.

@article{Chin1996DepressedSM,
  title={Depressed smooth muscle contractility after massive intestinal resection in rat: role of alterations in muscarinic receptor status or source of calcium for excitation-contraction coupling.},
  author={Bessie W C Chin and Dr. T.-Y. Tan and Robert B. Scott},
  journal={Canadian journal of physiology and pharmacology},
  year={1996},
  volume={74 11},
  pages={1187-95}
}
Following massive intestinal resection (removal of 75% of the mid-jejunoileum) in the rat, there is a significant reduction in the in vitro tonic contractile response of the remaining jejunal circular smooth muscle in response to stimulation with the muscarinic agonist bethanechol. The aim of these experiments was to determine if this alteration is specific to muscarinic excitation and occurs as a result of changes in the source and availability of calcium required for excitation-contraction… CONTINUE READING
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