Depressed neutrophil motility in patients with recurrent herpes simplex virus infections: in vitro restoration with levamisole.

@article{Rabson1977DepressedNM,
  title={Depressed neutrophil motility in patients with recurrent herpes simplex virus infections: in vitro restoration with levamisole.},
  author={Arthur R. Rabson and David A. Whiting and Ronald T. Anderson and Alan Glover and Hendrik J. Koornhof},
  journal={The Journal of infectious diseases},
  year={1977},
  volume={135 1},
  pages={113-6}
}
The random migration and chemotaxis of neutrophils from 10 patients with recurrent infections with herpes simplex virus were assessed. Chemotaxis to endotoxin-activated serum was markedly diminished in this group, but random migration was only mildly reduced, and chemotaxis to hydrolyzed casein was normal. The effects of the immunostimulant drug levamisole on the chemotaxis of neutrophils were assessed both in vitro and in patients after 150 mg of the drug was taken daily for three days. The… CONTINUE READING