Depressed natural killer cell cytotoxicity against Plasmodium falciparum-infected erythrocytes during first pregnancies.

@article{BouyouAkotet2004DepressedNK,
  title={Depressed natural killer cell cytotoxicity against Plasmodium falciparum-infected erythrocytes during first pregnancies.},
  author={Marielle Karine Bouyou-Akotet and Saadou Issifou and Jean François Mey{\'e} and Maryvonne Kombila and Edouard Ngou-Milama and Adrian J F Luty and Peter Gottfried Kremsner and Elie Mavoungou},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2004},
  volume={38 3},
  pages={342-7}
}
We measured natural killer (NK) cell cytotoxicity and cortisol and prolactin concentrations in peripheral venous blood samples obtained from pregnant Gabonese women at the time of delivery. The NK cell-mediated cytotoxicity against Plasmodium falciparum-infected erythrocytes in vitro was lower in samples obtained from primiparous women than in samples obtained from multiparous women; cortisol concentrations were significantly higher in primiparous women than in multiparous women, and prolactin… CONTINUE READING

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