Depressed lymphoproliferative response in mixed leukocyte reaction after Mis-locus alloimmunization.

Abstract

The proliferation of BALB/C lymphocytes preimmunized with Mis or H-2 incompatible cells in response to alloantigens was studied. The results show that preimmunization with Mis-incompatible spleen cells inhibits the lymphoproliferative response against alloantigens whereas preimmunization with H-2 incompatible spleen cells enhances it. It is suggested that Mis coded determinants activate suppressor mechanisms responsible for the unresponsiveness of these preimmunized lymphocytes against alloantigens.

Cite this paper

@article{Solana1984DepressedLR, title={Depressed lymphoproliferative response in mixed leukocyte reaction after Mis-locus alloimmunization.}, author={Rafael Sabido Solana and Mar{\'i}a Carmen Alonso and Mercedes de la Fuente and Juan A Paniagua and Robert Rojas and Javier Pe{\~n}a}, journal={Revista española de fisiología}, year={1984}, volume={40 1}, pages={1-4} }