Depressed Function of a Ouabain‐Sensitive Sodium‐Potassium Pump in Blood Vessels from Renal Hypertensive Dogs

@article{Overbeck1976DepressedFO,
  title={Depressed Function of a Ouabain‐Sensitive Sodium‐Potassium Pump in Blood Vessels from Renal Hypertensive Dogs},
  author={H. Overbeck and M. Pamnani and T. Akera and Theodore M. Brody and F. Haddy},
  journal={Circulation Research},
  year={1976},
  volume={38},
  pages={II-48–II-52}
}
Vasodilator responses to acute intra-arterial infusions of K+ are attenuated in dogs with chronic one-kidney perinephritic hypertension in rats with chronic two-kidney Goldblatt hypertension, and in men with essential hypertension. There is evidence that K+ evokes vasodilation by stimulating vascular smooth muscle membrane Na+-K+-activated adenosine triphosphatase, thereby increasing activity of the cellular Na+-K+ electrogenic pump. We therefore proposed that there may be an underlying… Expand
162 Citations
Sodium‐Potassium Pump Activity in Reduced Renal‐Mass Hypertension
  • 57
  • PDF
Hypertensive Dog Plasma Inhibits the Na+‐K+ Pump of Cultured Vascular Smooth MuscleXS
  • 9
  • PDF
The sodium-potassium pump in volume expanded hypertension.
  • 109
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 43 REFERENCES
Vasodilator responses to K+ in genetic hypertensive and in renal hypertensive rats.
  • 10
Attenuated vasodilator responses to K+ in essential hypertensive men.
  • 72
  • PDF
Similar Vasoconstrictor Responses to Calcium in Normotensive and Essential Hypertensive Men 1 2
  • 18
Cell potential and the sodium-potassium pump in vascular smooth muscle.
  • 34
Increased Cardiac Output as a Contributory Factor in Experimental Renal Hypertension in Dogs
  • 121
  • PDF
Decreased Venous Compliance in Dogs with Chronic Renal Hypertension 1
  • G. Simon, M. Pamnani, H. Overbeck
  • Medicine
  • Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine
  • 1976
  • 25
...
1
2
3
4
5
...