Depot testosterone with etonogestrel implants result in induction of azoospermia in all men for long-term contraception.

@article{Brady2004DepotTW,
  title={Depot testosterone with etonogestrel implants result in induction of azoospermia in all men for long-term contraception.},
  author={Brian M Brady and Melanie J Walton and N Hollow and Andrew T Kicman and David T Baird and Richard A. Anderson},
  journal={Human reproduction},
  year={2004},
  volume={19 11},
  pages={2658-67}
}
BACKGROUND Combined testosterone and progestogen preparations are a promising approach to male hormonal contraception. We investigated the effect of s.c. etonogestrel with depot testosterone on spermatogenesis in normal men over a period of 48 weeks. METHODS Fifteen healthy men received three s.c. 68 mg etonogestrel implants. Testosterone pellets (400 mg) were administered at 12 weekly intervals. RESULTS Nine men completed 48 weeks of treatment. Four subjects chose to discontinue after 6… CONTINUE READING
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A clinical trial of 7a-methyl-19-nortestosterone implants for possible use as a long-acting contraception in men

  • S von Eckardstein, G Noé, +8 authors K Sundaram
  • J Clin Endocrinol Metab
  • 2003
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