Deposition of salicylic acid into hamster sebaceous.

  title={Deposition of salicylic acid into hamster sebaceous.},
  author={Monica R Motwani and Linda D. Rhein and Joel L. Zatz},
  journal={Journal of cosmetic science},
  volume={55 6},
In an earlier paper, we identified vehicles that are miscible with sebum, using differential scanning calorimetry (DSC). In this paper, the potential of these vehicles to deliver salicylic acid (SA) into the sebum-filled follicles of hamster ears is examined. The main objective of this study is to correlate the melting transitions of a model sebum with the follicular delivery of SA, using two different types of vehicles (fatty and polar). Generally, the fatty vehicles show higher deposition… CONTINUE READING