Deposition, turnover, and release of CENH3 at Arabidopsis centromeres

  title={Deposition, turnover, and release of CENH3 at Arabidopsis centromeres},
  author={Inna Lermontova and Twan Rutten and Ingo Schubert},
The kinetochore is a complex multiprotein structure located at centromeres and required for the proper segregation of chromosomes during mitosis and meiosis. An important role in kinetochore assembly and function plays the centromeric histone H3 variant (CENH3). Cell cycle stage of CENH3 deposition to centromeres varies between different organisms. We confirmed by in vivo studies that deposition of Arabidopsis CENH3 takes place at centromeres during G2 and demonstrated that additionally a low… CONTINUE READING


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