Deposition, retention, and translocation of ultrafine particles from the central airways and lung periphery.

@article{Mller2008DepositionRA,
  title={Deposition, retention, and translocation of ultrafine particles from the central airways and lung periphery.},
  author={W. M{\"o}ller and K. Felten and K. Sommerer and G. Scheuch and Gabriele Meyer and P. Meyer and K. H{\"a}ussinger and W. Kreyling},
  journal={American journal of respiratory and critical care medicine},
  year={2008},
  volume={177 4},
  pages={
          426-32
        }
}
RATIONALE Little is known about clearance of ultrafine carbon particles from the different regions of the human lung. These particles may accumulate and present a health hazard because of their high surface area. OBJECTIVES Technetium Tc 99m ((99m)Tc)-radiolabeled 100-nm-diameter carbon particles were inhaled by healthy nonsmokers, asymptomatic smokers, and by patients with chronic obstructive pulmonary disease (COPD). METHODS Using a bolus inhalation technique, particle deposition was… Expand
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