Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF.


STUDY QUESTION Are significant abnormalities in outward (K(+)) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success? SUMMARY ANSWER Negligible outward conductance (≈5% of patients) or an enhanced inward conductance (≈4% of… (More)
DOI: 10.1093/humrep/dew056