Depolarization-induced suppression of a glycinergic synapse in the superior olivary complex by endocannabinoids.

@article{Trattner2013DepolarizationinducedSO,
  title={Depolarization-induced suppression of a glycinergic synapse in the superior olivary complex by endocannabinoids.},
  author={Barbara Trattner and Sarah Berner and Benedikt Grothe and Lars Kunz},
  journal={Journal of neurochemistry},
  year={2013},
  volume={127 1},
  pages={78-90}
}
The neuronal endocannabinoid system is known to depress synaptic inputs retrogradely in an activity-dependent manner. This mechanism has been generally described for excitatory glutamatergic and inhibitory GABAergic synapses. Here, we report that neurones in the auditory brainstem of the Mongolian gerbil (Meriones unguiculatus) retrogradely regulate the strength of their inputs via the endocannabinoid system. By means of whole-cell patch-clamp recordings, we found that retrograde… CONTINUE READING