Depolarization-dependent effect of flavonoids in rat uterine smooth muscle contraction elicited by CaCl2.

@article{Revuelta1997DepolarizationdependentEO,
  title={Depolarization-dependent effect of flavonoids in rat uterine smooth muscle contraction elicited by CaCl2.},
  author={Mati Revuelta and Bego{\~n}a Cantabrana and Agust{\'i}n Hidalgo},
  journal={General pharmacology},
  year={1997},
  volume={29 5},
  pages={847-57}
}
1. The effects of the flavonoids genistein (3-60 microM), kaempferol (3-60 microM) and quercetin (1-100 microM) on KCl (60 mM)-induced tonic contraction in rat uterus and their modifications with the inhibitor of cAMP-dependent protein kinases (TPCK, 3 microM), the inhibitor of ornithine decarboxylase [alpha-difluoromethyl ornithine (DFMO), 10 mM] and the polyamine spermine (1 mM) have been assayed. The effects of the three flavonoids were also studied on the contraction elicited by CaCl2 (30… CONTINUE READING
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