Depolarization and laminin independently enable bFGF to promote neuronal survival through different second messenger pathways.

@article{Schmidt1995DepolarizationAL,
  title={Depolarization and laminin independently enable bFGF to promote neuronal survival through different second messenger pathways.},
  author={M. F. Schmidt and Stanley B. Kater},
  journal={Developmental biology},
  year={1995},
  volume={168 2},
  pages={235-46}
}
This study presents evidence that cellular responsiveness to the neurotrophic factor basic fibroblast growth factor (bFGF) can be achieved by at least two classes of agents using different initial second messenger pathways. Embryonic chick ciliary ganglion neurons plated on polyornithine normally undergo rapid cell death in culture and could not be rescued by addition of bFGF. Similarly, neither exposure to laminin alone nor low levels of depolarization alone was sufficient to promote neuronal… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

Vertebrate Eye Development

Elizabeth Fini
Results and Problems in Cell Differentiation • 2000
View 1 Excerpt

Membrane recycling in the neuronal growth cone revealed by FM1-43 labeling.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…