Depletion of yeast ribosomal proteins L16 or rp59 disrupts ribosome assembly

@article{Moritz1990DepletionOY,
  title={Depletion of yeast ribosomal proteins L16 or rp59 disrupts ribosome assembly},
  author={M Moritz and Amanda G. Paulovich and Yi Fang Tsay and John L. Woolford},
  journal={The Journal of Cell Biology},
  year={1990},
  volume={111},
  pages={2261 - 2274}
}
Two strains of Saccharomyces cerevisiae were constructed that are conditional for synthesis of the 60S ribosomal subunit protein, L16, or the 40S ribosomal subunit protein, rp59. These strains were used to determine the effects of depriving cells of either of these ribosomal proteins on ribosome assembly and on the synthesis and stability of other ribosomal proteins and ribosomal RNAs. Termination of synthesis of either protein leads to diminished accumulation of the subunit into which it… CONTINUE READING