Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells

@inproceedings{Amin2008DepletionON,
  title={Depletion of nucleophosmin leads to distortion of nucleolar and nuclear structures in HeLa cells},
  author={Mohammed Abdullahel Amin and Sachihiro Matsunaga and Susumu Uchiyama and Kiichi Fukui},
  booktitle={The Biochemical journal},
  year={2008}
}
NPM (nucleophosmin; also known as B23) is an abundantly and ubiquitously expressed multifunctional nucleolar phosphoprotein, which is involved in numerous cellular processes, including ribosome biogenesis, protein chaperoning and centrosome duplication; however, the role of NPM in the cell cycle still remains unknown. In the present study, we show dynamic localization of NPM throughout the cell cycle of HeLa cells. Using a combination of RNAi (RNA interference) and three-dimensional microscopy… CONTINUE READING

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protein Lem2 is a critical for normal nuclear envelope morphology

  • A M., S. Matsunaga, +4 authors K. Fukui
  • Biochem. Biophys. Res
  • 2007

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