Depletion of four nitrofuran antibiotics and their tissue-bound metabolites in porcine tissues and determination using LC-MS/MS and HPLC-UV.

@article{Cooper2005DepletionOF,
  title={Depletion of four nitrofuran antibiotics and their tissue-bound metabolites in porcine tissues and determination using LC-MS/MS and HPLC-UV.},
  author={Kevin M Cooper and Patrick P. J. Mulder and Johannes A van Rhijn and Lor{\'e}na Kovacsics and Robert J McCracken and Paul B. Young and D. Glenn Kennedy},
  journal={Food additives and contaminants},
  year={2005},
  volume={22 5},
  pages={406-14}
}
Depletion of the nitrofuran antibiotics furazolidone, furaltadone, nitrofurantoin and nitrofurazone and their tissue-bound metabolites AOZ, AMOZ, AHD and SEM from pig muscle, liver and kidney tissues is described. Groups of pigs were given feed medicated with one of the nitrofuran drugs at a therapeutic concentration (400?mg?kg(-1)) for ten days. Animals were slaughtered at intervals and tissue samples collected for analysis for six weeks following withdrawal of medicated feed. These samples… CONTINUE READING
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