Depletion and repletion kinetics of vitamin C in humans.

  title={Depletion and repletion kinetics of vitamin C in humans.},
  author={James Blanchard},
  journal={The Journal of nutrition},
  volume={121 2},
Depletion and repletion profiles of vitamin C were determined in young and elderly males and females. Plasma vitamin C concentrations were determined upon entry into the study, once each week during a 5-wk period of dietary restriction (10 mg/day) of the vitamin and twice each week during a 2.5-wk period of supplementation with 500 mg/d. The rate constant (K) and the half-life of the depletion phase (t1/2) were determined. Other values calculated included the mean plasma vitamin C concentration… CONTINUE READING
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