Depersonalization disorder: pharmacological approaches

  title={Depersonalization disorder: pharmacological approaches},
  author={M. Sierra},
  journal={Expert Review of Neurotherapeutics},
  pages={19 - 26}
  • M. Sierra
  • Published 2008
  • Psychology, Medicine
  • Expert Review of Neurotherapeutics
  • Depersonalization disorder (DPD) is a chronic and distressing condition with a prevalence in the general population between 0.8 and 2%. Several neurobiological studies in the last decade have shown that patients have suppressed limbic activation to emotional stimuli. Such findings are in line with a model which suggests that the condition is generated by an anxiety-triggered, ’hard-wired’ inhibitory response to threat. Such a mechanism would ensure the preservation of adaptive behavior, during… CONTINUE READING
    35 Citations

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