• DOI:10.1586/14737175.8.1.19
Corpus ID: 22180718

Depersonalization disorder: pharmacological approaches

@article{Sierra2008DepersonalizationDP,
  title={Depersonalization disorder: pharmacological approaches},
  author={M. Sierra},
  journal={Expert Review of Neurotherapeutics},
  year={2008},
  volume={8},
  pages={19 - 26}
}

M. Sierra

Published 2008

Psychology, Medicine

Expert Review of Neurotherapeutics

Depersonalization disorder (DPD) is a chronic and distressing condition with a prevalence in the general population between 0.8 and 2%. Several neurobiological studies in the last decade have shown that patients have suppressed limbic activation to emotional stimuli. Such findings are in line with a model which suggests that the condition is generated by an anxiety-triggered, ’hard-wired’ inhibitory response to threat. Such a mechanism would ensure the preservation of adaptive behavior, during… CONTINUE READING

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