Dependence of myocardial hypothermia tolerance on sources of activator calcium.

@article{Wang1997DependenceOM,
  title={Dependence of myocardial hypothermia tolerance on sources of activator calcium.},
  author={Shi Qiang Wang and Y H Huang and Katharine S Liu and Zeng Zhou},
  journal={Cryobiology},
  year={1997},
  volume={35 3},
  pages={193-200}
}
To determine the relationship between cardiac hypothermia tolerance and the sources of activator calcium, we selectively modified either the sarcolemmal calcium permeability by nifedipine or the sarcoplasmic reticulum function by caffeine in papillary muscles from both the rat, as a cold sensitive model, and the ground squirrel, Citellus dauricus, a deep hibernator. Both force-interval relationship and cooling performance were investigated. At 25 degrees C, the slope of the force-interval curve… CONTINUE READING
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