Dependence of histamine release from rat mast cells on adenosine triphosphate

using pure populations of rat mast cells, the relation of the ATP content of the cells to histamine release induced by compound 48/80 has been studied. Variable ATP levels in the mast cells have been produced by incubation with appropriate concentrations of oligomycin. The dose-response curves of oligomycin for the inhibition of histamine release and for… CONTINUE READING