Dependence of calcium permeability of sarcoplasmic reticulum vesicles on external and internal calcium ion concentrations.

@article{Katz1977DependenceOC,
  title={Dependence of calcium permeability of sarcoplasmic reticulum vesicles on external and internal calcium ion concentrations.},
  author={Arnold M. Katz and Denis Repke and J. S. Dunnett and Wilhelm Hasselbach},
  journal={The Journal of biological chemistry},
  year={1977},
  volume={252 6},
  pages={1950-6}
}
The ability of sarcoplasmic reticulum vesicles to retain calcium following ATP-supported calcium uptake in the presence of the calcium-precipitating anions oxalate and phosphate depends on Cao (calcium ion concentration outside the vesicles) and Cai (calcium ion concentration within the vesicles). Calcium efflux rates at any level of Cai are accelerated when Cao is increased. Higher Cao at the time that calcium uptake reactions reach steady state is associated with a spontaneous calcium release… CONTINUE READING