Dependence of calcium influx in neocortical cells on temporal structure of depolarization, number of spikes, and blockade of NMDA receptors.

@article{Balaban2004DependenceOC,
  title={Dependence of calcium influx in neocortical cells on temporal structure of depolarization, number of spikes, and blockade of NMDA receptors.},
  author={Pavel M Balaban and Marina Chistiakova and Aleksey Malyshev and Maxim Volgushev},
  journal={Journal of neuroscience research},
  year={2004},
  volume={76 4},
  pages={481-7}
}
Increase of intracellular [Ca(2+)] evoked by action potentials in a cell can induce long-term synaptic plasticity even without concomitant presynaptic stimulation. We used optical recording of the fluorescence of a Ca(2+)-indicator Oregon Green to investigate whether differences in results obtained with modifications of that purely postsynaptic induction protocol could be due to differential Ca(2+) influx. We compared changes of the somatic [Ca(2+)] in layer II-III pyramidal cells in slices of… CONTINUE READING

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