Dependence of Yeast Pre-mRNA 3′-End Processing on CFT1: A Sequence Homolog of the Mammalian AAUAAA Binding Factor

@article{Stumpf1996DependenceOY,
  title={Dependence of Yeast Pre-mRNA 3′-End Processing on CFT1: A Sequence Homolog of the Mammalian AAUAAA Binding Factor},
  author={G. Stumpf and H. Domdey},
  journal={Science},
  year={1996},
  volume={274},
  pages={1517 - 1520}
}
3′-End formation of pre-mRNA in yeast and mammals follows a similar but distinct pathway. In Saccharomyces cerevisiae, the cleavage reaction can be reconstituted by two activities called cleavage factor I and II (CFI and CFII). A CFII component, designated CFT1 (cleavage factor two) was identified by its sequence similarity to the AAUAAA-binding subunit of the mammalian cleavage and polyadenylation specificity factor (CPSF), even though the AAUAAA signal sequence appears to play no role in… Expand
3'-End processing of pre-mRNA in eukaryotes.
Protein factors in pre-mRNA 3′-end processing
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
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4
5
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References

SHOWING 1-10 OF 28 REFERENCES
Separation of factors required for cleavage and polyadenylation of yeast pre-mRNA.
...
1
2
3
...