Corpus ID: 41555380

Deoxyribonucleic acid biosynthesis in mitochondria. Purification and general properties of rat liver mitochondrial deoxyribonucleic acid polymerase.

@article{Meyer1970DeoxyribonucleicAB,
  title={Deoxyribonucleic acid biosynthesis in mitochondria. Purification and general properties of rat liver mitochondrial deoxyribonucleic acid polymerase.},
  author={R. R. Meyer and M. Simpson},
  journal={The Journal of biological chemistry},
  year={1970},
  volume={245 13},
  pages={
          3426-35
        }
}
  • R. R. Meyer, M. Simpson
  • Published 1970
  • Biology, Medicine
  • The Journal of biological chemistry
  • Abstract Deoxyribonucleic acid polymerase has been purified 3550-fold from rat liver mitochondria, which computes to 14,000-fold based on whole liver as the starting material. The enzyme is essentially free of deoxyribonuclease, phosphomonoesterase, phosphodiesterase, deoxyguanosine triphosphatase, ribonuclease, nuclear DNA polymerase, and terminal nucleotidyltransferase activities. It is stable when stored at -125° or colder, but loses activity rapidly at higher temperatures and during… CONTINUE READING
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