Dentin glycoprotein: the protein in the middle of the dentin sialophosphoprotein chimera.

@article{Yamakoshi2005DentinGT,
  title={Dentin glycoprotein: the protein in the middle of the dentin sialophosphoprotein chimera.},
  author={Yasuo Yamakoshi and Jan C. C. Hu and Makoto Fukae and Hengmin Zhang and James P. Simmer},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 17},
  pages={17472-9}
}
Dentin sialophosphoprotein (DSPP) is a major secretory product of odontoblasts and is critical for proper dentin formation. DSPP is believed to be processed into only two structural/functional domains: dentin sialoprotein (DSP) and dentin phosphoprotein (DPP). Here we report the isolation and characterization of a third domain of DSPP, designated dentin glycoprotein (DGP). DGP was isolated from a guanidine/EDTA extract of porcine tooth dentin by ion exchange, hydroxyapatite affinity, size… CONTINUE READING
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