Dentate gyrus and spatial behaviour

  title={Dentate gyrus and spatial behaviour},
  author={Gilberto Fernando Xavier and Val{\'e}ria Catelli Infantozzi Costa},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  • G. XavierV. C. I. Costa
  • Published 1 August 2009
  • Biology, Psychology
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry

Tables from this paper

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Critical maturational period of new neurons in adult dentate gyrus for their involvement in memory formation

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Hippocampal Neurogenesis Levels Predict WATERMAZE Search Strategies in the Aging Brain

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Melatonin increases dendritogenesis in the hilus of hippocampal organotypic cultures

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Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories

The cells and circuits of the dentate gyrus are examined, and evidence indicating that this brain region has multiple mnemonic functions is discussed, to explore mechanistic links between the cellular and network properties of, and the computations performed by, the DG.

Adult hippocampal neurogenesis and its role in cognition.

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Dentate gyrus‐selective colchicine lesion and disruption of performance in spatial tasks: Difficulties in “place strategy” because of a lack of flexibility in the use of environmental cues?

DG‐lesioned rats exhibit a marked difficulty in place strategies, particularly evident when these rats are required to deal with one‐trial place learning in a familiar environment, such as in the working memory version of the water maze task, which requires flexibility in the use of previously acquired information.

Evidence that granule cells generated in the dentate gyrus of adult rats extend axonal projections

Examination of autoradiographs from these brains reveals that 3H-TdR labeled cells within the granule cell layer of the dentate gyrus are often labeled with the retrograde tracer as well, which indicates that within the mature hippocampal formation, newly generated dentate granule cells are capable of extending axonal projections for considerable distances.

Cognitive Performances and Locomotor Activity Following Dentate Granule Cell Damage in Rats: Role of Lesion Extent and Type of Memory Tested

Intradentate injection of colchicine is one of the techniques used to destroy granule cells. This study compared the behavioral effects of various amounts of colchicine (1.0, 3.0, and 6.0 microg; Col

Cochicine-induced granule cell loss in rat hippocampus: Selective behavioral and histological alterations

The role of hippocampal subregions in detecting spatial novelty.

The results suggest that the DG-CA3 network is essential in detecting novelty for spatial, but not for individual object, information.

Running enhances neurogenesis, learning, and long-term potentiation in mice.

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Dentate gyrus-selective colchicine lesion and performance in temporal and spatial tasks

Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge

Most of the spatial information exhibited by hippocampal pyramidal cells is likely to be transmitted from the cortex by routes other than the traditional “trisynaptic circuit”, including the direct projections from entorhinal layers II and III to CA3 and CA1, respectively.