Dental pulp tissue engineering with bFGF-incorporated silk fibroin scaffolds.

@article{Yang2015DentalPT,
  title={Dental pulp tissue engineering with bFGF-incorporated silk fibroin scaffolds.},
  author={Jing-Wen Yang and Yu-feng Zhang and Zhe-Yi Sun and Guang-Tai Song and Zhi Chen},
  journal={Journal of biomaterials applications},
  year={2015},
  volume={30 2},
  pages={221-9}
}
The clinical translation of regenerative endodontics demands further development of suitable scaffolds. Here, we assessed the possibility of using silk fibroin scaffold for pulp regeneration with dental pulp stem cells (DPSCs) and basic fibroblast growth factor (bFGF) in ectopic root canal transplantation model. Porous silk fibroin scaffolds were fabricated using freeze-drying technique (with or without bFGF incorporation), and characterized by scanning electron microscopy (SEM) and Fourier… CONTINUE READING

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