Dental pulp tissue engineering of pulpotomized rat molars with bone marrow mesenchymal stem cells

@article{Ito2016DentalPT,
  title={Dental pulp tissue engineering of pulpotomized rat molars with bone marrow mesenchymal stem cells},
  author={Takafumi Ito and Tomoatsu Kaneko and Yukiko Sueyama and Reika Kaneko and Takashi Okiji},
  journal={Odontology},
  year={2016},
  volume={105},
  pages={392-397}
}
The major goal of dental pulp tissue engineering is to enable the healing of inflamed tissue or to replace necrotic pulp tissue with newly formed dental pulp tissue. Here, we report a protocol for pulp tissue engineering in vivo in pulpotomized rat teeth using constructs of rat bone marrow mesenchymal stem cells, preformed biodegradable scaffolds, and hydrogel. The constructs were implanted into pulpotomized pulp chambers for 3, 7, or 14 days. At 3 days, cells were located mainly along the… CONTINUE READING
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